Progress of bilirubin in the mechanism of atherosclerosis
10.20039/j.cnki.1007-3949.2024.08.010
- VernacularTitle:胆红素在动脉粥样硬化机制中的研究进展
- Author:
Weilei GONG
1
;
Lei WANG
;
Yang YU
;
Peiqing LIU
Author Information
1. 山东第一医科大学(山东省医学科学院)药学院(药物研究所),山东省济南市 250117
- Keywords:
bilirubin;
atherosclerosis;
oxidative stress;
inflammation;
lipid deposition
- From:
Chinese Journal of Arteriosclerosis
2024;32(8):712-718
- CountryChina
- Language:Chinese
-
Abstract:
Atherosclerosis is a chronic vascular wall disease and the most common pathological change in cardiovas-cular disease.Its pathogenesis is closely related to inflammation,oxidative stress,and lipid deposition.Bilirubin itself has biological activities such as antioxidant and anti-inflammatory effects,and has a protective effect on the cardiovascular system.This article summarizes the mechanism of bilirubin in the development of atherosclerosis and its research pro-gress.
