Association between triglyceride-glucose index and hypertension in middle-aged and older adults
10.20039/j.cnki.1007-3949.2024.07.005
- VernacularTitle:中老年人群甘油三酯葡萄糖乘积指数与高血压的关联研究
- Author:
Jianyong ZHAO
1
;
Chunyue GUO
;
Cui SONG
Author Information
1. 天津中医药大学第二附属医院重症医学科,天津市 300250
- Keywords:
triglyceride-glucose index;
hypertension;
middle-aged and older adults
- From:
Chinese Journal of Arteriosclerosis
2024;32(7):583-589
- CountryChina
- Language:Chinese
-
Abstract:
Aim To investigate the relationship between triglyceride-glucose(TyG)index and the risk of hy-pertension in middle-aged and older adults in China,and to provide scientific basis for the prevention and treatment of hypertension.Methods Data were obtained from the China health and retirement longitudinal study(CHARLS)in 2011.A multi-stage stratified sampling method was used to select participants.Restricted cubic spline regression model was used to analyze the dose-response relationship between TyG index and the risk of hypertension.Multivariate unconditional Logistic regression model was used to evaluate the association between TyG index and the risk of hyperten-sion.Results A total of 9 987 subjects were included in the analysis,with an average age of(59.16±9.43)years,including 4 707 males(47.13％).The restricted cubic spline regression model showed that the risk of hypertension in-creased with the elevation of TyG index,and there was a linear association(overall association test P＜0.000 1,non-linear association test P=0.201 9).The results of multivariate Logistic regression model showed that compared with Q1(TyG index＜8.23),the OR(95％CI)of hypertension with Q2(8.23≤ TyG index＜8.59),Q3(8.59 ≤ TyG index＜9.04)and Q4(TyG index≥9.04),were 1.09(0.95～1.26),1.53(1.33～1.76)and 1.77(1.52～2.06),respectively.Conclusions With the increase of TyG index,the risk of hypertension gradually increased.TyG index may be an inde-pendent risk factor of hypertension.
