The effect of wall shear stress on atherosclerosis and aneurysm
10.20039/j.cnki.1007-3949.2024.05.012
- VernacularTitle:血管壁面剪切应力对动脉粥样硬化和动脉瘤的影响
- Author:
Shuyan LI
1
;
Xinyu TAO
;
Chen QU
Author Information
1. 南京医科大学第二附属医院老年医学科,江苏省南京市 210011
- Keywords:
wall shear stress;
atherosclerosis;
aneurysm;
hemodynamics
- From:
Chinese Journal of Arteriosclerosis
2024;32(5):451-455
- CountryChina
- Language:Chinese
-
Abstract:
Wall shear stress is an important parameter in hemodynamics.Normal wall shear stress maintains the physiological state of blood vessels,while abnormal wall shear stress is closely related to the pathological progression of ath-erosclerosis and aneurysm,which is one of the risk factors for the occurrence of malignant cardiovascular and cerebrovascu-lar events.Abnormal wall shear stress destroys the normal function of endothelial cells through different pathogenesis,mediates the initiation and evolution of these two diseases.This article reviews the impact of wall shear stress on athero-sclerosis and aneurysm based on literature research in recent years.
