Correlation between early pupillary light reflex reduction and delirium in mechanically ventilated ICU patients receiving sedation
10.3760/cma.j.cn115682-20211228-05875
- VernacularTitle:接受镇静的ICU机械通气患者早期瞳孔对光反射降低与谵妄的相关性分析
- Author:
Yingmei QI
1
;
Jinghui CAO
;
Shaomin SHI
;
Ronghui JIN
Author Information
1. 吉林大学中日联谊医院护理部，长春 130033
- Keywords:
Delirium;
Respiration, artificial;
Quantitative pupillometry;
Neurologic function
- From:
Chinese Journal of Modern Nursing
2022;28(24):3312-3315
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the correlation between early pupillary light reflex reduction and delirium in mechanically ventilated patients receiving sedation in the Intensive Care Unit (ICU) .Methods:From December 2020 to March 2021, convenience sampling was used to select 97 ICU patients with mechanical ventilation who received sedation in the China-Japan Union Hospital of Jilin University as the research subject. On the second to fourth days of the patient's stay in the ICU, the quantitative pupillary light reflex (q-PLR) and pupillary contraction velocity (CV) of the patients after photostimulation were measured by an automatic infrared pupillometer with a frequency of two times a day. Patients were assessed using the Richmond Agitation-Sedation Scale (RASS) . When the RASS score was≥-2, the patient was screened for delirium using the Confusion Assessment Method for Intensive Care Unit (CAM-ICU) with a frequency of two times a day. According to the screening results, patients were divided into delirium group and non-delirium group.Results:The incidence of delirium in 97 ICU mechanically ventilated patients who received sedation was 58.76% (57/97) . Binomial Logistic regression showed that q-PLR on the second day was an influencing factor for delirium in mechanically ventilated ICU patients receiving sedation ( P<0.05) . Conclusions:Early pupillary light reflex reduction is associated with delirium in mechanically ventilated ICU patients receiving sedation.
