Meta-analysis of effects of exercise rehabilitation on pulmonary function, aerobic capacity and quality of life in children with bronchial asthma
10.3760/cma.j.cn115682-20211026-04829
- VernacularTitle:运动康复对支气管哮喘患儿肺功能、有氧能力及生存质量影响的Meta分析
- Author:
Shuhui YANG
1
;
Yulin LIU
;
Qian WANG
;
Lijingzi WANG
;
Xiaoyan CHE
;
Zhengxiu LUO
Author Information
1. 重庆医科大学附属儿童医院两江院区呼吸科/儿童发育疾病研究教育部重点实验室/国家儿童健康与疾病临床医学研究中心/儿童发育重大疾病国家国际科技合作基地/儿科学重庆市重点实验室,重庆 401120
- Keywords:
Child;
Bronchial asthma;
Exercise rehabilitation;
Pulmonary function;
Aerobic capacity;
Quality of life;
Meta-analysis
- From:
Chinese Journal of Modern Nursing
2022;28(21):2808-2816
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of exercise rehabilitation on pulmonary function, aerobic capacity and quality of life in children with bronchial asthma.Methods:According to the PICOS principle, China National Knowledge Infrastructure (CNKI) , VIP, Wanfang Database, SinoMed, Web of Science, Cochrane Library, PubMed, Embase and CINAHL were used to search for all Chinese and English randomized controlled trials on the effect of exercise rehabilitation on children with bronchial asthma from January 1, 2000 to December 23, 2021. The Cochrane manual was used to systematically review the literature. Meta-analysis was performed using RevMan 5.3.Results:Finally, 15 articles were included, with a total of 936 subjects. Meta-analysis results showed that exercise rehabilitation could improve percentage of forced vital capacity in the predicted value (FVC%) [mean difference ( MD) =2.75, 95% confidence interval ( CI) (1.22-4.28) , P=0.000 4] , percentage of forced expiratory volume in one second in predicted value (FEV 1%) [standardized mean difference ( SMD) =0.22, 95% CI (0.07-0.36) , P=0.003] , percentage of peak expiratory flow in the predicted value (PEF%) [ MD=7.15, 95% CI (3.30-11.00) , P=0.000 3] , maximum oxygen uptake (VO 2max) [ MD=5.86, 95% CI (2.53-9.19) , P=0.000 6] and quality of life [ MD=0.67, 95% CI (0.43-0.91) , P<0.000 01] , but there was no statistically significant difference in improving the ratio of FEV 1% to FVC% (FEV 1/FVC%) [ MD=-0.97, 95% CI (-3.55-1.61) , P=0.46] . Conclusions:Exercise rehabilitation can improve partial pulmonary function, aerobic capacity and quality of life in children with asthma. However, it still needs to continue to be promoted in the clinical practice, in order to verify its effectiveness with more high-quality research.