Epidemiological and clinical characteristics of brucellosis in Xinjiang Uygur Autonomous Region
10.3760/cma.j.cn231583-20230327-00070
- VernacularTitle:新疆维吾尔自治区布鲁氏菌病流行病学及临床特征分析
- Author:
Zhiwei LI
1
;
Lingling WANG
;
Shuling LI
;
Qian WANG
;
Shuting YANG
;
Xuewei TONG
;
Bingli WANG
;
Peipei LU
;
Changmin WANG
Author Information
1. 新疆维吾尔自治区人民医院临床检验中心，乌鲁木齐 830001
- Keywords:
Brucella;
Epidemiology;
Clinical characteristic;
Laboratory examination
- From:
Chinese Journal of Endemiology
2024;43(7):575-579
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the epidemiological and clinical characteristics of brucellosis in Xinjiang Uygur Autonomous Region.Methods:A retrospective analysis method was used to collect medical records of 581 patients with brucellosis who visited the Xinjiang Uygur Autonomous Regional People's Hospital from January 2009 to December 2019. Demographic and epidemiological characteristics, clinical symptoms and signs, and laboratory test results of the patients were analyzed.Results:Among 581 patients with brucellosis, the male to female ratio was 2.8 ∶ 1.0 (428 ∶ 153). The age was (44.41 ± 16.25) years old, ranging from 1 - 83 years old, and mainly concentrated in 35 - 60 years old, accounting for 70.91% (412/581). The ethnic distribution was dominated by Uyghur, accounting for 50.60% (294/581). The occupational distribution was mainly farmers, accounting for 43.20% (251/581). A total of 186 patients had a clear history of contact with cattle and sheep, accounting for 32.01% (186/581). The clinical stage was dominated by patients in the acute stage, accounting for 55.25% (321/581). There were 48 cases of complications, accounting for 8.26%(48/581). The main clinical symptom of brucellosis patients was pain and fever, accounting for 73.67% (428/581) and 66.61% (387/581), respectively. Laboratory tests were dominated by increased blood sedimentation and C-reactive protein, accounting for 29.09% (169/581) and 23.06% (134/581), respectively. The positive rate of Brucella culture was low, accounting for 4.48% (26/581). Conclusions:The majority of brucellosis patients in Xinjiang Uygur Autonomous Region are young and middle-aged males, with the main occupation being farmers. The clinical symptoms are mostly pain and fever. The positive rate of Brucella culture in patients is relatively low. It is recommended to combine epidemiological and clinical features for diagnosis to reduce missed diagnosis and misdiagnosis, and detect and treat it early.
