Current clinical application of glomerular filtration rate assessment methods in pediatric populations
10.7499/j.issn.1008-8830.2401011
- VernacularTitle:肾小球滤过率评估方法在儿童人群中的应用现状
- Author:
Zi-Sai WANG
1
;
Sheng-Feng WANG
;
Ming-Yi ZHAO
;
Qing-Nan HE
Author Information
1. 中南大学湘雅三医院儿科,湖南长沙 410013
- Keywords:
Glomerular filtration rate;
Creatinine;
Cystatin C;
Renal function assessment;
Child
- From:
Chinese Journal of Contemporary Pediatrics
2024;26(9):1002-1008
- CountryChina
- Language:Chinese
-
Abstract:
Glomerular filtration rate(GFR)is a critical indicator of renal function assessment,which exhibits age-dependency in children and may differ from adults under various disease conditions.In recent years,there has been a growing focus on GFR among scholars,with an increasing number of clinical studies dedicated to refining and optimizing GFR estimation to span all pediatric age groups.However,the methods and assessment equations for estimating GFR may vary under different disease conditions,affecting the accuracy and applicability of assessments.This article reviews the peculiarities of renal function in children,explores GFR measurement methods,and evaluates the application of various GFR assessment equations in pediatric clinical practice,providing a reference for clinical assessment of renal function in children.
