Moxifloxacin treatment for Mycoplasma hominis meningitis in an extremely preterm infant
10.7499/j.issn.1008-8830.2312016
- VernacularTitle:莫西沙星治疗超早产儿人型支原体脑膜炎1例
- Author:
Wei-Ying MAO
1
;
Jiang-Er LAN
;
Ming-Yu GAN
;
Xun-Jie ZHANG
;
Hui YU
;
Li-Yuan HU
;
Rong ZHANG
;
Yun CAO
;
Mi-Li XIAO
Author Information
1. 国家儿童医学中心/复旦大学附属儿科医院新生儿科,上海 201102
- Keywords:
Purulent meningitis;
Mycoplasma hominis;
Moxifloxacin;
Extremely preterm infant
- From:
Chinese Journal of Contemporary Pediatrics
2024;26(4):432-436
- CountryChina
- Language:Chinese
-
Abstract:
The patient,a male newborn,was admitted to the hospital 2 hours after birth due to prematurity(gestational age 27+5 weeks)and respiratory distress occurring 2 hours postnatally.After admission,the infant developed fever and elevated C-reactive protein levels.On the fourth day after birth,metagenomic next-generation sequencing of cerebrospinal fluid indicated a positive result for Mycoplasma hominis(9 898 reads).On the eighth day,a retest of cerebrospinal fluid metagenomics confirmed Mycoplasma hominis(56 806 reads).The diagnosis of purulent meningitis caused by Mycoplasma hominis was established,and the antibiotic treatment was switched to moxifloxacin[5 mg/(kg·day)]administered intravenously for a total of 4 weeks.After treatment,the patient's cerebrospinal fluid tests returned to normal,and he was discharged as cured on the 76th day after birth.This article focuses on the diagnosis and treatment of neonatal Mycoplasma hominis purulent meningitis,introducing the multidisciplinary diagnosis and treatment of the condition in extremely preterm infants.[Chinese Journal of Contemporary Pediatrics,2024,26(4):432-436]
