Systematic review and Meta-analysis of application effect of progressive resistance training in breast cancer
10.3760/cma.j.cn115682-20210614-02601
- VernacularTitle:渐进性抗阻训练在乳腺癌中应用效果的系统评价和Meta分析
- Author:
Chi ZHANG
1
;
Shiqi ZHAO
;
Shaowen TANG
;
Hua YOU
Author Information
1. 南京医科大学护理学院，南京 211166
- Keywords:
Breast neoplasms;
Progressive resistance training;
Systematic review;
Meta-analysis
- From:
Chinese Journal of Modern Nursing
2022;28(13):1717-1726
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the application effect of progressive resistance training (PRT) in breast cancer patients.Methods:PubMed, Web of Science, Embase, Medline, Cochrane Library, CNKI, Wanfang Data Knowledge Service platform, VIP and SinoMed databases were searched for randomized controlled trial (RCT) of PRT in breast cancer patients. The retrieval period was from the establishment of databases to November 30, 2020. Meta-analysis was performed using Revman 5.3 and Stata 16.1.Results:A total of 22 RCT were included. Meta-analysis showed that PRT could improve muscle strength [grip strength ( MD=1.43, 95% CI 0.57-2.30, P=0.001) , supine lifting force ( MD=13.0, 95% CI 9.39-16.61, P<0.000 01) , leg lifting force ( MD=43.88, 95% CI 27.85-59.91, P<0.000 01) ], shoulder flexion ( MD=9.62, 95% CI 5.16-14.09, P<0.000 1) , lean body weight ( MD=1.03, 95% CI 0.71-1.35, P<0.000 01) , quality of life ( SMD=0.51, 95% CI 0.25-0.78, P=0.000 1) . PRT could reduce the number of symptoms of upper limb lymphedema in breast cancer patients ( SMD=-0.23, 95% CI -0.42--0.04, P=0.020) , severity of symptoms ( SMD=-0.26, 95% CI -0.44--0.07, P=0.006) , body fat percentage ( MD=-1.49, 95% CI -1.94--1.04, P<0.000 01) , fat content ( MD=-0.87, 95% CI -1.48--0.26, P=0.005) , but there were no statistically significant differences in shoulder joint abduction, extension, body weight and body mass index ( P>0.05) . Descriptive analysis showed that PRT could reduce the incidence of upper limb lymphedema to a certain extent. Conclusions:The existing evidence shows that compared with the control group, PRT can improve the muscle strength, shoulder anterior flexion, lean body weight content and quality of life of patients with breast cancer and reduce the number and severity of upper extremity lymphedema symptoms, body fat percentage and fat mass.
