Clinical practice guidelines for meropenem therapy in neonatal sepsis(2024)
10.7499/j.issn.1008-8830.2309059
- VernacularTitle:美罗培南治疗新生儿脓毒症的临床实践指南(2024年版)
- Author:
Guideline Development Group of Clinical Practice Guidelines for Meropenem Therapy in Neonatal Sepsis
1
;
Peking University Third Hospital
;
Editorial Department of Chinese Journal of Contemporary Pediatrics
;
X-M TONG
;
W-H ZHOU
;
K-H YANG
Author Information
1. 北京大学第三医院儿科
- Keywords:
Meropenem;
Sepsis;
Clinical practice guideline;
Neonate
- From:
Chinese Journal of Contemporary Pediatrics
2024;26(2):107-117
- CountryChina
- Language:Chinese
-
Abstract:
Meropenem is one of the most widely used special-grade antimicrobial agents in the treatment of neonatal sepsis.However,its irrational use has led to an increasingly severe problem of bacterial multidrug resistance.The guideline was developed following standardized methods and procedures,and provides 12 recommendations specifically addressing 9 clinical issues.The recommendations cover various aspects of meropenem use in neonates,including timing of administration,recommended dosage,extended infusion,monitoring and assessment,antimicrobial adjustment strategies,treatment duration,and treatment strategies for carbapenem-resistant Enterobacteriaceae infections.The aim of the guideline is to provide evidence-based recommendations and guidance for the rational use of meropenem in neonates with sepsis.[Chinese Journal of Contemporary Pediatrics,2024,26(2):107-117]