Effects of Early Nutrition After Birth on the Development of Small Intestine and Body Growth in Rats with Intrauterine Growth Retardation
10.3969/j.issn.1008-8830.2003.03.004
- VernacularTitle:早期营养干预对宫内生长迟缓大鼠小肠发育及体格生长的影响
- Author:
DENG HUI-YING
1
;
QIU XIAO-SHAN
Author Information
1. First Affiliated Hospital Sun Yat-sen University
- Keywords:
Intrauterine growth retardation;
Nutrition;
Small intestine;
Growth-development;
Disaccharidase;
Rats
- From:
Chinese Journal of Contemporary Pediatrics
2003;5(3):197-200
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of early nutrition on the development of physique and small intestine inrats with intrauterine growth retardation (IUGR). Methods Eight normal pubs fed with normal protein diet (20 % )were used as normal controls. The IUGR pups were assigned into normal protein diet group (IC group), low-protein dietgroup (IL group) and high protein diet group (IH group). On the 1st, 21st and 28th day after birth respectively, theweight and length of small intestine (SI), the body weight and length, and the activities of disaccharidase weremeasured. Results The body weight and length, weight and length of SI in rats with IUGR at birth were allsignificantly lower than those in normal rats ( P ＜ 0.05). Body length, body weight, length and weight of SI in ILgroup were all lower than those in IC, IH and normal control groups in the first 4 weeks after birth. The physique andsmall intestine in IH group caught up growth quickly, the body weight in the 4th week reached the normal value. In thethird week, the lactase activity in IL and IH groups were higher than that in normal control group ( P ＜0.05). In the4th week, the sucrase activity in IL group was lower than that in normal control ( P ＜ 0.05). Conclusions Earlynutrition after birth has an important effect on the development of physique and SI in rats with IUGR.
