Diagnostic Significance of Cardial Troponin T and Neuro-peptide Y in Hyperthyroic Heart Disease
10.3969/j.issn.1008-8830.2001.01.004
- VernacularTitle:神经肽Y及心肌肌钙蛋白T在甲状腺功能亢进性心脏病中的意义
- Author:
Hong WANG
1
;
Zhi-Chao WANG
;
Zhuo ZHOU
Author Information
1. Second Clinical College Medical University
- From:
Chinese Journal of Contemporary Pediatrics
2001;3(1):14-16
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of cardial troponin T (cTnT) and neuro-peptide Y (NTY) in hyperthyroic heart disease. Methods The concentrations of serum cTnT and NTY were measured by ELISA method in 23 patients with hyperthyroidism, and were correlated with the myocardial systolic functions (cardic index, CI; ejective fration, EF) before and after the treatment. Results The concentrations of cTnT, NTY, FT3, FT4 and blood pressure (BP) at the beginning were 0.13±0.04 ng/L, 192.8±7.1 ng/L, 36.79±4.94 ng/L, 52.96±16.18 ng/L and 123.69±10.06 mmHg, which after the treatment were 0.06±0.03 ng/L, 140.2±5.1 ng/L, 11.52±4.74 ng/L, 26.81±5.18 ng/L and 105.00±8.66 mmHg while TSH was lower at the beginning (1.21±0.45 U/L) than after the treatment (1.84±0.29 U/L) in hyperthyroidism (t=2.185, 2.08, 13.3, 4.53 and 4.84, respectively). The myocardial systolic functions were damaged in hyperthyroidism. The interrelations between NTY and CI, EF were negative in hyperthyroidism (r=-0.333 and -0.203, Y=276.21-21.785X; Y=0.632-2.902X, respectively). Conclusions The concentrations of NTY and cTnT are higher in hyperthyroic heart disease. The higher the NTY and cTnT concentrations, the worse the myocardial systolic functions.
