Primarily results of quantification of serum phenytoin in patients with epilepsy
- Author:
Nga Viet Phan
- Publication Type:Journal Article
- Keywords:
epilepsy
- MeSH:
Serum;
Phenytoin;
Epilepsy
- From:Journal of Practical Medicine
2002;435(11):38-40
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
This study was carried out on 36 blood samples of epileptic patients, between the ages of 6 and 15, in Army Hospital 103 during 9/2000 - 6/2001, who used a monotherapy - phenytoin. The results of quantitative analysis of serum concentration of drug in the treatment range, under the treatment range and above the treatment range among patients with disease free was 72.41%, 13.78% and 13.8%. 80% of patients used phenytorin at dose of 5-8mg/kg/day had a serum concentration in the treatment range. The dose of phenytoin can be increased increasingly in cases without responding to the treatment while the drug concentration closely reached the treatment range until the defects found.
