Progress in relationship between expression of solute carrier family 3 member 2,and disulfidptosis,ferroptosis and tumors
10.3969/j.issn.1000-4718.2024.00.024
- VernacularTitle:溶质载体家族3成员2表达与双硫死亡、铁死亡及肿瘤关系的研究进展
- Author:
Huan MA
1
;
Jiuju DAI
;
Yanli YANG
;
Zubang ZHOU
Author Information
1. 甘肃中医药大学第一临床医学院,甘肃 兰州 730000
- Keywords:
solute carrier family 3 member 2;
disulfidptosis;
ferroptosis;
tumor
- From:
Chinese Journal of Pathophysiology
2024;40(9):1772-1776
- CountryChina
- Language:Chinese
-
Abstract:
Ferroptosis and disulfidpthosis are associated with various diseases.Ferroptosis is distinguished by abnormal accumulation of iron ions and lipid reactive oxygen species,while disulfidptosis is marked by abnormal accumu-lation of disulfides.Solute carrier family 3 member 2(SLC3A2),a component of the solute carrier family,is implicated not only involved in the regulation of tumor cell proliferation,migration,invasion and apoptosis,but also in the processes of ferroptosis and disulfidptosis,playing a pivotal role in tumor growth and progression.This article provides an overview of the latest advancements in understanding the relationship between SLC3A2 and ferroptosis,disulfidptosis and tumors,aiming to establish a theoretical basis for targeted cancer therapies.
