The clinical effects of body mass index in patients with acute myocardial infarction after percutaneous coronary intervention.
- Author:
Seon Young JEONG
1
;
Jung Ae RHEE
;
Myung Ho JEONG
;
Seon Ho HWANG
;
Nam Sik YOON
;
Seo Na HONG
;
Sang Rok LEE
;
Kye Hun KIM
;
Jae Youn MOON
;
Young Joon HONG
;
Hyung Wook PARK
;
Ju Han KIM
;
Young Keun AHN
;
Jeong Gwan CHO
;
Jong Chun PARK
;
Jung Chaee KANG
Author Information
1. The Heart Center of Chonnam National University Hospital, Chonnam National University Research Institute of Medical Sciences, Gwangju, Korea. myungho@chollian.net
- Publication Type:Original Article
- Keywords:
Myocardial infarction;
Obesity;
Prognosis
- MeSH:
Body Mass Index*;
Cholesterol;
Coronary Artery Disease;
Diagnosis;
Follow-Up Studies;
Humans;
Hyperlipidemias;
Hypertension;
Myocardial Infarction*;
Obesity;
Percutaneous Coronary Intervention*;
Prevalence;
Prognosis;
Risk Factors;
Triglycerides
- From:Korean Journal of Medicine
2007;73(6):603-610
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Obesity is one of the major risk factors for coronary artery disease. However, the long-term clinical effects of obesity after percutaneus coronary intervention (PCI) in Korean patients with acute myocardial infarction (AMI) have not been sufficiently evaluated. METHODS: A total of 309 patients (mean age 60.5+/-11.3 years, M:F=243:66) that underwent PCI with a diagnosis of AMI between February 2002 and June 2006. Thepatients were divided into two groups according to the body mass index (BMI): group I (n=194; BMI <25 kg/m2; mean age 61.7+/-11.1 years, M:F=151:43) and group II (n=115; BMI> or =25 kg/m2, mean age 58.2+/-11.3 years, M:F=92:23). Clinical characteristics and risk factors, and major adverse cardiac events during a six-month follow-up were compared between patients in the two gropus. RESULTS: The mean age of group I patients was older than that of group II patients (61.7+/-11.1 years vs. 58.6+/-11.5 years, p=0.017). The prevalence of hypertension was higher in group II patients (75/194, 38.7% vs.59/115, 51.3%, p=0.033) and hyperlipidemia was more prevalent in group II patients (75/194, 38.7% vs. 60/115, 52.2%, p=0.024). The levels of total cholesterol (184.3+/-39.9 mg/dL vs. 201.4+/-42.6 mg/dL, p=0.001), triglycerides (121.2+/-61.6 mg/dL vs. 147.1+/-96.2 mg/dL, p=0.005), low-density lipoprotein-cholesterol (120.3+/-35.1 mg/dL vs. 134.1+/-37.8 mg/dL, p=0.002) were lower in group I patients than in group II patients. The restenosis rate on a follow-up coronary angiogram was higher in group II patients (18/69, 26.1%) than in group I patients (14/109, 12.8%, p=0.025). CONCLUSIONS: Obesity is associated with hyperlipidemia and hypertension in patients with AMI. The restenosis rate after PCI was higher in obese AMI patients.
