Meta-analysis of efficacy and safety of totally implantable access port and peripherally inserted central catheter in adult patients with hematological tumor undergoing chemotherapy
10.3760/cma.j.cn115682-20210316-01153
- VernacularTitle:植入式静脉输液港与PICC在成人血液肿瘤化疗患者中应用疗效和安全性的Meta分析
- Author:
Xinhong DING
1
;
Xiaomei QI
Author Information
1. 江苏省无锡市第二人民医院血液科，无锡 214002
- Keywords:
Hematological tumors;
Totally implantable access port;
PICC;
Meta-analysis
- From:
Chinese Journal of Modern Nursing
2022;28(2):233-239
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the application effects of totally implantable access port (TIAP) and peripherally inserted central catheter (PICC) in adult patients with hematological tumor undergoing chemotherapy.Methods:PubMed, Embase, Cochrane Library, CNKI, Wanfang Database and VIP database were searched by computer for all randomized controlled trials of TIAP and PICC in patients receiving chemotherapy for hematological tumors, and the search time was from the establishment of the databases to March 1, 2021. Statistical software STATA 15.0 was used for Meta-analysis. The success rate of one-time catheterization, the incidence of unplanned extubation, the maintenance time of the tubes, incidence of complications and quality of life scores were compared between the two groups.Results:A total of 11 studies were included, including adult patients with hematological tumor undergoing chemotherapy (371 in the TIAP group and 383 in the PICC group) . The success rate of one-time catheterization ( RR=1.11, 95% CI 1.03-1.20) , the incidence of unplanned extubation ( RR=0.37, 95% CI 0.16-0.88) , pipeline maintenance time ( WMD=-3.89, 95% CI -4.95--2.83) , complication rate ( RR=0.25, 95% CI 0.16-0.40) , quality of life score ( WMD=4.82, 95% CI 2.14-7.50) of the TIAP group were better than those of the PICC group, and the differences were statistically significant ( P<0.05) . Conclusions:TIAP catheterization success rate, pipeline maintenance time, complication rate, and quality of life all show advantages, but due to the small sample size of some indicators, further research is needed.
