Analysis of influencing factors and predictive model construction of persistent atelectasis after thoracoscopic radical resection of lung cancer
10.3760/cma.j.cn115682-20210217-00710
- VernacularTitle:胸腔镜下肺癌根治术后持续性肺不张发生的影响因素分析及预测模型构建
- Author:
Xiaoxia YAN
1
;
Hongting LIU
;
Chunjuan ZHOU
;
Tingting SI
;
Yanjun MAO
Author Information
1. 同济大学附属上海市肺科医院胸外科，上海 200433
- Keywords:
Lung neoplasm;
Surgery;
Atelectasis;
Risk prediction model;
High-risk population
- From:
Chinese Journal of Modern Nursing
2022;28(1):27-31
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the risk factors of persistent atelectasis in patients undergoing radical resection of lung cancer and construct a predictive model for persistent atelectasis after lung cancer surgery.Methods:Using the convenient sampling method, a total of 332 patients undergoing video-assisted thoracic surgery (VATS) at Department of Thoracic Surgery in Shanghai Pulmonary Hospital affiliated to Tongji University were selected from July 2019 to June 2020. Patients were divided into non-persistent atelectasis group ( n=104) and persistent atelectasis group ( n=228). Logistic regression analysis was used to investigate the independent predictors of perioperative persistent atelectasis in patients undergoing radical lung cancer surgery, and a predictive model was established. Results:Body mass index, tumor TNM stage, pathological category, history of chronic obstructive pulmonary disease and preoperative neoadjuvant therapy (chemotherapy, immunotherapy, and targeted therapy) were independent predictors of persistent atelectasis after VATS ( P<0.05). Based on the above predictive factors, a predictive model of persistent atelectasis during the perioperative period was established. Logit ( P) = 2.015 + 0.836 × body mass index + 2.515 × history of chronic obstructive pulmonary disease-1.451 × pathological type-1.700 (stage Ⅰ) /1.146 (stage Ⅱ) × tumor TNM stage + 3.312 × neoadjuvant therapy history. Conclusions:The predictive model constructed in this study can provide a theoretical basis for screening high-risk patients with persistent atelectasis and provide a reference for clinical medical staff to take preventive treatment and nursing care for high-risk patients in time.
