Correlation between voice handicap index and motor symptoms,cognitive function and respiratory function in Parkinson disease
10.19845/j.cnki.zfysjjbzz.2024.0186
- VernacularTitle:帕金森病嗓音障碍指数与运动症状、认知功能和呼吸功能的相关性分析
- Author:
Yiheng WANG
1
;
Boyan FANG
;
Detao MENG
Author Information
1. 首都医科大学附属北京康复医院,北京 100144
- Keywords:
Parkinson disease;
Voice handicap;
Motor symptom;
Cognitive function;
Respiratory function
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(11):977-981
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between the voice handicap index(VHI)and motor symp-toms,cognitive function,and respiratory function in Parkinson disease(PD).Methods A total of 124 patients with PD hospitalized in the Parkinson Medical Center,Beijing Rehabilitation Hospital,Capital Medical University from April 2020 to March 2023 were included,and the general data of the subjects were collected.We used the Hoehn and Yahr scale to determine the clinical stage of the PD patients;the Movement Disorder Society Unified Parkinson Disease Rating Scale Part Ⅲ(MDS-UPDRS Ⅲ)to assess the motor symptoms of the patients;the VHI-10 to assess voice status;the Parkinson's Disease-Cognitive Rating Scale(PD-CRS),the Trail Making Test(TMT),and the Digit Symbol Substitution Test(DSST)to assess cognitive function;and the forced vital capacity(FVC),forced expiratory volume in the 1st second(FEV1),FEV1/FVC,and maximal voluntary ventilation(MVV)to measure respiratory function.The correlation between voice sta-tus and motor symptoms,cognitive function,and respiratory function in patients with PD using Spearman correlation analy-sis.Results The VHI-10 score of the PD patients was positively correlated with the MDS-UPDRS Ⅲ score,facial expression score,rigidity score,axial symptom score,and time to complete the TMT(r=0.20,0.22,0.18,0.31,0.22;P＜0.05),and was negatively correlated with the DSST score and FEV1/FVC(r=-0.24,-0.24;P＜0.05).Conclusion Voice impairment in PD patients may be influenced by multiple factors and may correlate with motor symptoms,cognitive function,and respira-tory function.
