Research advances in the effect of deep brain stimulation on eye movement in patients with Parkinson disease

VernacularTitle:脑深部电刺激术对帕金森病患者眼球运动影响的研究进展
Author: Chenhui PEI ¹ ; Tingting ZHANG ; Zhanhua LIANG
Author Information

1. 大连医科大学附属第一医院神经内科,辽宁大连 116000
Keywords: Parkinson disease; Deep brain stimulation; Eye movement; Postoperative programming
From: Journal of Apoplexy and Nervous Diseases 2024;41(11):969-972
CountryChina
Language:Chinese
Abstract: Deep brain stimulation(DBS)has become an established technique for the treatment of neurodegenerative diseases such as Parkinson disease(PD).This technique significantly improves the clinical symptoms of PD patients by directly stimulating specific basal ganglia nuclei with implanted electrodes,but its physiological mechanism of action remains unclear.The control mechanisms of eye movement involve the cerebral cortex and basal ganglia,which are extensively overlapped with the targeted network of DBS,but there are relatively few studies on the combined analysis of DBS and eye movement.This article explores the interaction mechanism between DBS and eye movement control to deeply understand the influence of DBS on eye movement function,which is of great significance for optimizing stimulation parameters and improving therapeutic effect.In addition,these studies provide new perspectives for revealing the mechanism of action of DBS and the pathophysiology of PD.