A systematic review of the effects of limited fluid intake on the prognosis of patients with heart failure
10.3760/cma.j.cn115682-20210412-01608
- VernacularTitle:限制液体摄入对心力衰竭患者预后影响的系统评价
- Author:
Weiyun WANG
1
;
Zejuan GU
;
Yanling HUANG
;
Ruhua ZHOU
;
Ziwen SU
;
Lei YANG
;
Changhong LIU
Author Information
1. 南京医科大学第一附属医院（江苏省人民医院）心脏大血管外科，南京 210029
- Keywords:
Heart failure;
Limited fluid intake;
Prognosis;
Meta-analysis;
Sequential analysis
- From:
Chinese Journal of Modern Nursing
2021;27(32):4407-4414
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically review the effects of limited fluid intake on the prognosis of patients with heart failure.Methods:RCTs about the effects of limited fluid intake on the prognosis of patients with heart failure published up to March 31, 2021 were retrieved from PubMed, The Cochrane Library, CINAHL, Embase, Web of Science, CNKI, Wanfang, VIP, and SinoMed. Two independent researchers were employed to extract data and evaluate the quality of included literature. Rev Man 5.3 was used for Meta-analysis, sequential analysis to evaluate the reliability and authenticity of the research results, and the Egger's test for publication bias.Results:A total of 7 articles were included, with a sample size of 867 cases. Meta-analysis showed that the body weight [ MD=-3.04, 95% CI (-4.70, -1.38) , P<0.001], B-type natriuretic peptide [ MD=-249.32, 95% CI (-305.00, -193.63) , P<0.001], blood creatinine [ MD=-22.03, 95% CI (-24.98, -19.09) , P<0.001], readmission rate [ OR=0.30, 95% CI (0.20, 0.45) , P<0.001] of the limited fluid intake group in the chronic phase of heart failure were lower than those in the control group; the body weight [ MD=1.41, 95% CI (-3.73, 6.55) , P=0.59], B-type natriuretic peptide [ MD=64.52, 95% CI (-50.01, 179.06) , P=0.27], serum creatinine [ MD=3.83, 95% CI (-9.69, 17.36) , P=0.58], readmission rate [ OR=1.21, 95% CI (0.65, 2.27) , P=0.55] of the acute fluid intake group were not statistically different from those in the control group. Conclusions:Limiting fluid intake in the chronic phase of heart failure can effectively improve the patients' heart and kidney function and the prognosis of the disease. In the acute phase of heart failure, it may be necessary to combine multiple treatments to keep the patients at the best volume state.
