Evidence-based nursing practice for prevention of oral mucositis in children with hematopoietic stem cell transplantation
10.3760/cma.j.cn115682-20210210-00693
- VernacularTitle:造血干细胞移植患儿口腔黏膜炎预防的循证护理实践
- Author:
Chunli WANG
1
;
Lianye LI
;
Rui LIANG
;
Fangjiao CHEN
;
Xinyi WU
;
Maoquan QIN
;
Ying GU
Author Information
1. 国家儿童医学中心 首都医科大学附属北京儿童医院血液肿瘤中心 100045
- Keywords:
Hematopoietic stem cell transplantation;
Children;
Prevention;
Oral mucositis;
Evidence-based nursing practice
- From:
Chinese Journal of Modern Nursing
2021;27(31):4239-4245
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To apply the best evidence for prevention of oral mucositis in children with hematopoietic stem cell transplantation (HSCT) to clinical practice and evaluate its efficacy.Methods:Evidence-based nursing method was applied to obtain the best evidence, the evidence quality review indexes were established and the obstacle factors were analyzed, and then the action strategy was constructed. Using the convenient sampling method, a total of 60 children who were admitted to HSCT ward of Beijing Children's Hospital of Capital Medical University and 14 nurses working in HSCT ward were selected as the research objects from August 2019 to October 2020. The children admitted from August 2019 to February 2020 were included in the control group, and children admitted from March to October 2020 were included in the experimental group, with 30 cases in each group. Children in the control group received routine preventive measures for oral mucositis, while children in the experimental group received preventive measures for oral mucositis constructed based on the best evidence. Before and after the application of the evidence, the nurses' knowledge of preventing oral mucositis in children with HSCT was investigated through self-developed test papers. The incidence of oral mucositis and parents' satisfaction with prevention measures for oral mucositis were compared between the two groups.Results:Evidence-based nursing practice used 10 pieces of evidence. The incidence of oral mucositis in the experimental group was 50% (15/30) , lower than 83% (25/30) in the control group, and the difference was statistically significant (χ 2=7.50, P < 0.05) . The score of satisfaction with for preventive measures of oral mucositis of parents in the experimental group was (4.96±0.05) , which was higher than (3.65±1.60) of the control group, and the difference was statistically significant ( t=-9.69, P<0.01) . After the application of the evidence, the score of nurses' knowledge of prevention of oral mucositis was (98.22±6.65) , which was higher than (78.72±12.03) before the application, and the difference was statistically significant ( t=5.30, P<0.01) . Conclusions:Management of oral mucositis in children with HSCT through evidence-based nursing practice can effectively reduce the incidence of oral mucositis in children, improve parents' satisfaction with prevention measures for oral mucositis and nurses' knowledge of prevention of oral mucositis.
