Research advances in the mechanism of action of repetitive transcranial magnetic stimulation in improving cogni-tive impairment in patients with Alzheimer disease
10.19845/j.cnki.zfysjjbzz.2024.0135
- VernacularTitle:重复经颅磁刺激改善阿尔茨海默病认知障碍作用机制的研究进展
- Author:
Xinmeng LI
1
;
Xuehua SUN
Author Information
1. 滨州医学院,山东 滨州 256600
- Keywords:
Repetitive transcranial magnetic stimulation;
Alzheimer disease;
Cognitive impairment;
Review
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(8):704-708
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer disease(AD)is a common neurodegenerative disease with overall cognitive deterioration and mental and behavioral disorders,and due to unknown etiology and pathogenesis of AD,there is currently no effective medi-cation for AD.As a new noninvasive neuromodulation method,repetitive transcranial magnetic stimulation(rTMS)can improve cognitive impairment in patients with AD by regulating multiple pathways such as neural activity,synaptic plastic-ity,neurotransmitters,and neurotrophic factors.This article reviews the studies on the mechanism of action of rTMS in the treatment of AD in recent years,in order to clarify the mechanisms of rTMS such as anti-oxidation and regulation of synaptic plasticity.
