Advances in the diagnosis and treatment of acute symptomatic seizures secondary to autoimmune encephalitis and autoimmune-related epilepsy
10.19845/j.cnki.zfysjjbzz.2024.0098
- VernacularTitle:自身免疫性脑炎急性症状性痫性发作和自身免疫相关性癫痫的诊治进展
- Author:
Wenlin SUN
1
;
Yinyin XIE
;
Tingting PENG
Author Information
1. 郑州大学第一附属医院,河南 郑州 450052
- Keywords:
Epilepsy;
Autoimmune encephalitis;
Acute symptomatic seizures;
Autoimmune-related epilepsy
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(6):515-520
- CountryChina
- Language:Chinese
-
Abstract:
Acute symptomatic seizures secondary to autoimmune encephalitis refers to seizures that occur during the active stage of immune-mediated encephalitis,and autoimmune-related epilepsy refers to disorders with an immune etiol-ogy and a long-term predisposition to unprovoked seizures.Both diseases often have poor response to antiepileptic drugs,and early identification of immune etiology and initiation of immunotherapy may help patients achieve a good prognosis.However,there are no guidelines for the use of drugs in patients with different types of symptomatic seizures,and there is also a lack of diagnostic criteria and treatment principles for autoimmune-related epilepsy.This article reviews and dis-cusses the two diseases from the aspects of possible pathogenesis,clinical manifestations,and recommended treatment methods,so as to provide a theoretical basis for diagnosis and treatment and help to determine future research directions.
