Mechanism of the Development of Follicles Based on Cellular Force Transducer
10.16156/j.1004-7220.2024.05.028
- VernacularTitle:基于细胞力传感器探索卵泡发育机制
- Author:
Qingqing YANG
1
;
Jifeng REN
;
Xin RUAN
;
Pengxu WANG
;
Xiaoying DONG
Author Information
1. 首都医科大学 中医药学院,北京 100069
- Keywords:
cellular force transducer;
follicle development;
cytoskeleton
- From:
Journal of Medical Biomechanics
2024;39(5):992-997
- CountryChina
- Language:Chinese
-
Abstract:
Cellular force transducer plays a crucial role in normal development of the follicles,which consists of integrin,focal adhesion,signal pathways and cytoskeleton.In follicle development,cellular force transducer converts force stimulation into biochemical signal,and activates the signal pathways to make cytoskeleton respond to stimulation.This process promotes various biological functions of germ cells,such as migration,meiosis and ovulation.This review summarizes the mechanism of follicles'development from two aspects,the role of cellular force transducer in the development of follicles and the related signal pathways,so as to provide a new idea for the further study of follicle development.
