Meta-analysis of the effects of intermittent oro-esophageal tube feeding in patients with dysphagia after stroke
10.3760/cma.j.cn115682-20201024-05894
- VernacularTitle:间歇性经口至食管管饲法在脑卒中后吞咽障碍患者中应用的Meta分析
- Author:
Peiyu ZHANG
1
;
Yushen DING
;
Yahong XU
Author Information
1. 首都医科大学2016级护理学院本科生,北京 100069
- Keywords:
Dysphagia;
Stroke;
Intermittent oro-esophageal tube feeding;
Meta-analysis
- From:
Chinese Journal of Modern Nursing
2021;27(25):3420-3426
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of intermittent oro-esophageal tube feeding (IOE) on the swallowing function, incidence of aspiration pneumonia, and nutritional status in patients with dysphagia after stroke.Methods:Randomized controlled trials (RCTs) published from the establishment of the database to October 1, 2020 were retrieved from PubMed, Embase, Web of Science, EBSCO, Elsevier, OVID, ProQuest, CNKI, VIP, and Wanfang database. Two researchers independently conducted literature search, screening, data extraction and quality evaluation based on systematic reviews using Cochrane 5.11. RevMan 5.3 was used for the Meta-analysis of the included literature.Results:A total of 21 articles were included, with a total sample size of 1 616, including 809 patients receiving IOE and 807 patients with nasal indwelling gastric tube feeding. The Meta-analysis showed that IOE could enhance the swallowing function of patients ( RR=1.31, 95% CI: 1.21-1.43, P<0.01) , reduce the incidence of aspiration pneumonia ( RR=0.43, 95% CI: 0.28-0.65, P<0.01) , increase hemoglobin content ( MD=6.73, 95% CI: 5.89-7.57, P<0.01) , serum total protein content ( MD=4.44, 95% CI: 3.69-5.20, P<0.01) , serum prealbumin content ( MD=17.45, 95% CI: 7.29-27.62, P<0.01) , and serum albumin content ( MD=1.72, 95% CI: 1.33-2.10, P<0.01) . Conclusions:IOE can improve the swallowing function, reduce the incidence of aspiration pneumonia, and improve the nutritional level of patients with dysphagia after stroke, which has positive significance in clinical practice.