Structure Design and Experimental Verification of a Degradable Vascular Anastomotic Device
10.16156/j.1004-7220.2024.03.021
- VernacularTitle:可降解血管吻合器的结构设计与实验验证
- Author:
Kaiyue XU
1
;
Xue CAI
;
Zhongxin HU
;
Qinxian GAO
;
Xupo XING
;
Chengli SONG
;
Lin MAO
Author Information
1. 上海理工大学健康科学与工程学院,现代微创医疗器械及技术教育部工程研究中心,上海 200093
- Keywords:
degradable high purity magnesium;
vascular anastomotic device;
end-to-end anastomosis;
pressure distance
- From:
Journal of Medical Biomechanics
2024;39(3):518-523
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the efficiency and quality of end-to-end anastomosis,a novel degradable vascular anastomotic device was designed,and the relationship between pressure distances and biomechanical properties of the anastomotic stoma was explored.Methods The three-dimensional(3D)structure of the vascular anastomotic device was designed and the prototype was fabricated with extruded high-purity magnesium.The finite element model of the end-to-end vascular anastomosis was established to study the stress distributions of the anastomotic end face under different pressure distances(0.4,0.5,0.6,0.7,and 0.8 mm)and their change rules.In vitro experiments were conducted to verify the rationality of the finite element results as well as the feasibility and effectiveness of the vascular anastomotic device.Results When the pressure distance was 0.6 mm,the anastomotic tensile force,and burst pressure could reach(11.79±0.64)N and(39.32±2.99)kPa,respectively,meeting the clinical requirement for the strength of vascular anastomosis,and with the minimal mechanical damages to tissues.Conclusions The device designed in this study can be used for vascular anastomosis by adjusting the pressure distance,and it can improve operation efficiency,reduce mechanical damage to tissues,and further improve the quality of anastomosis.These results provide an essential reference for the design of degradable vascular anastomotic devices.
