A Case of Synovial Sarcoma Associated with Multiple Distant Metastasis.
- Author:
Jae Wang KIM
1
;
Hyun Wook KANG
;
Kwang Joong KIM
Author Information
1. Department of Dermatology, Cheju National University, College of Medicine, Jeju, Korea. rulidroxim@hanmail.net
- Publication Type:Case Report
- Keywords:
Synovial sarcoma;
Metastasis
- MeSH:
Abdomen;
Aged;
Cytogenetic Analysis;
Fibrosarcoma;
Humans;
Neoplasm Metastasis*;
RNA;
Sarcoma;
Sarcoma, Synovial*
- From:Korean Journal of Dermatology
2004;42(9):1176-1182
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Synovial sarcoma (SS) is a rare high grade soft tissue sarcoma with unusual epithelial differentiation. SS does not arise from synovial tissue, but rather originates from pluripotential mesenchymal cells. Three histomorphologic subtypes of SS have been described: biphasic, monophasic, and poorly differentiated. Typically, biphasic SS is composed of epitheloid cells forming pseudoglandular spaces and spindle cells resembling fibrosarcoma. We report a rare case of a 65-year-old man who presented with two asymptomatic masses on his abdomen and axillary regions. The pertinent histopathologic, immunohistochemical, cytogenetic analysis and radiographic examinations represented monophasic fibrous SS with multiple visceral metastasis. We also found SYT-SSX fusion gene transcript specific for SS using RNA samples taken from the lesional tissues.
