A Case of Premature Infant with Hyperthyroidism
10.3870/j.issn.1004-0781.2024.12.018
- VernacularTitle:早产儿甲状腺功能亢进1例
- Author:
Wenfang TANG
1
,
2
;
Lin ZHU
;
Jing WANG
;
Yanlei XU
;
Wei LIU
Author Information
1. 华中科技大学同济医学院附属同济医院新生儿科,武汉 430030
2. 武汉市汉阳医院新生儿科,武汉 430050
- Keywords:
Premature;
Neonatal;
Hyperthyroidism;
Diagnosis and treatment
- From:
Herald of Medicine
2024;43(12):1987-1990
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve clinicians'understanding of the diagnosis and treatment of neonatal hyperthyroidism which is rare in clinical practice.Methods The clinical data of a neonatal hyperthyroidism case diagnosed and treated was retrospectively analyzed,and the relevant literature was reviewed.Results A female infant,borned at 32 weeks and 6 days of gestation,exhibited dyspnea,a rapid heart rate,hepatosplenomegaly,thrombocytopenia,cholestasis,and abnormal liver function that continued to deteriorate after birth.She was later diagnosed with neonatal hyperthyroidism after undergoing thyroid function and antibody tests.After treated with methimazole,propranolol and other symptomatic supportive therapies,the infant's symptoms improved and she was discharged in good health.Conclusions The clinical manifestations of neonatal hyperthyroidism are non-specific and the symptoms are atypical.Therefore,when encountering symptoms such as growth retardation,tachycardia,cardiac insufficiency,tachypnea,thrombocytopenia,liver injury,hepatosplenomegaly,and a small head circumference,it is essential to consider the possibility of congenital hyperthyroidism.Timely thyroid function and antibody tests should be conducted to confirm the diagnosis,followed by early drug intervention to enhance the prognosis.
