Infrared Spectra Analysis of Rubber Substrate and Film in Common Pharmaceutical Packaging Materials
10.3870/j.issn.1004-0781.2024.11.010
- VernacularTitle:常见橡胶类药包材基材和膜材红外光谱解析
- Author:
Dandan WANG
1
;
Jun XU
;
Wenxu GUO
;
Yue CHEN
;
Hui YU
;
Lei CHEN
Author Information
1. 浙江省食品药品检验研究院,浙江省药品接触材料质量控制研究重点实验室,杭州 310052
- Keywords:
Pharmaceutical packaging materials;
Rubber;
Infrared spectra;
Analysis
- From:
Herald of Medicine
2024;43(11):1759-1764
- CountryChina
- Language:Chinese
-
Abstract:
Objective To record and analyze the infrared spectra of rubber substrate and film in common pharmaceutical packaging materials,and to provide technical support and reference for the infrared spectra identification of rubber pharmaceutical packaging materials in the national standards system.Methods The infrared spectra of the rubber substrate and film were recorded by the Fourier transform infrared(FT-IR)-attenuated total reflection(ATR)method.The main absorption peaks in the spectra were assigned,the vibration forms were analyzed,and the influencing factors of infrared spectra were discussed.Results The infrared spectra of silicone rubber,polyisoprene rubber,halogenated butyl rubber,ethylene-tetrafluoroethylene copolymer(ETFE),tetrafluoroethylene-hexafluoropropylene copolymer(FEP)and p-xylene were analyzed.Conclusion The production formula of rubber pharmaceutical packaging materials is complex and diverse.Factors such as test methods,rubber product production formula,ATR crystal materials,and silicone oil will affect the results of infrared spectra.
