Study on the predictive value of total cholesterol / high density lipoprotein cholesterol ratio for new-onset ischemic stroke in patients with coronary heart disease
10.3760/cma.j.cn115682-20201127-06426
- VernacularTitle:胆固醇与高密度脂蛋白比值对冠心病患者发生缺血性脑卒中的预测价值
- Author:
Qingyun ZHANG
1
;
Dandan SUN
;
Fen WANG
;
Quanliang WANG
;
Wenqing WANG
;
Ruijuan QIAN
;
Jie KANG
;
Tongxiu HU
;
Tao LIANG
Author Information
1. 济宁医学院附属医院心内一科，济宁 272100
- Keywords:
Coronary heart disease;
Cholesterol to high density lipoprotein ratio;
Ischemic stroke
- From:
Chinese Journal of Modern Nursing
2021;27(19):2596-2599
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the predictive value of total cholesterol / high density lipoprotein cholesterol ratio (TC/HDL) for ischemic stroke in patients with coronary heart disease (CHD) .Methods:A total of 1 983 inpatients with CHD in the Affiliated Hospital of Jining Medical University from January 1, 2017 to December 31, 2017 were selected as subjects by cluster sampling method. The clinical data were collected and followed up prospectively for 2 years.Results:During the 2-year follow-up period, 36 cases of ischemic stroke occurred in patients with CHD, and the incidence rate was 1.82% (36/1 983) . There was a curvilinear relationship between TC/HDL and ischemic stroke in male patients with CHD, and the tipping point was 3.84.When TC / HDL was less than 3.84, TC / HDL was negatively correlated with the incidence of ischemic stroke. The incidence of ischemic stroke decreased by 72% for each additional unit of TC/HDL ( P=0.049) . When TC/HDL was over 3.84, there was no correlation between TC / HDL and the incidence of ischemic stroke ( P=0.267) . There was a curvilinear relationship between TC/HDL and ischemic stroke in female patients with CHD, and the tipping point was 2.81. When TC / HDL was less than 2.81, TC / HDL was negatively correlated with the incidence of ischemic stroke. The incidence of ischemic stroke decreased by 99% for each additional unit of TC/HDL ( P=0.019) . When TC/HDL was over 2.81, there was no correlation between TC / HDL and the incidence of ischemic stroke ( P=0.110) . Conclusions:TC/HDL has different thresholds in predicting ischemic stroke in CHD patients with different genders, which has a certain clinical significance in predicting the prognosis of patients with coronary heart disease.
