Literature Analysis of 23 Cases of Anaphylactic Shock Induced by Iohexol Injection
10.3870/j.issn.1004-0781.2024.10.025
- VernacularTitle:23例碘海醇注射液致过敏性休克文献分析
- Author:
Erxia SHI
1
;
Zhongyan ZHOU
;
Laiyun YUN
;
Yuntana WU
Author Information
1. 呼和浩特市第一医院 药剂科,呼和浩特 010030
- Keywords:
Iohexol injection;
Allergic shock;
Adverse drug reactions
- From:
Herald of Medicine
2024;43(10):1680-1683
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the cases of allergic shock induced by iohexol injection,analyze the characteristics of adverse drug reactions(ADRs),and identify potential influencing factors,ensureing the safety of clinical medication.Methods A literature review and bibliometric analysis were conducted on 23 cases of allergic reactions induced by iohexol injections reported in China from 2010 to 2023.Results Among the cases of allergic reactions induced by iohexol injections,17 cases(73.91% )occurred in males,while 6 cases(26.09% )occurred in females.Individuals aged from 41 to 80 years accounted for a significant proportion(82.61% ).Systemic damage was observed in 8 cases(34.78% ),neurological damage in 7 cases(30.43% ),respiratory and circulatory system damage in 5 cases(21.74% ),and skin and appendage involvement in 3 cases(13.04% ).The majority of allergic reactions had a rapid onset(72.91% ).Patients with pre-existing chronic illnesses and other medical conditions had a higher occurrence rate(82.61% ).Conclusions Iohexol injection can lead to allergic reactions influenced by multiple factors.Healthcare professionals should closely monitor adverse reactions,especially severe ones like allergic shock.
