Clinical Pharmacy Services for Paternal Drug Exposure Based on A Pregnancy Drug Registry Platform
10.3870/j.issn.1004-0781.2024.10.023
- VernacularTitle:基于妊娠用药登记平台的父方药物暴露临床药学服务
- Author:
Dan ZHENG
1
;
Kejing WANG
;
Zongjie LYU
;
Xiaohong CHEN
;
Lin CHEN
Author Information
1. 重庆市妇幼保健院(重庆医科大学附属妇女儿童医院)药学部,重庆 401147
- Keywords:
Pateral drug exposure;
Pregnancy registries for medication;
Pharmacist-managed clinic;
Medication consultation;
Pharmacy services
- From:
Herald of Medicine
2024;43(10):1668-1671
- CountryChina
- Language:Chinese
-
Abstract:
Objective To communicate the paternal medication behaviors and patterns during the peri-pregnant period in China and to explore the types of pharmaceutical care services that clinical pharmacists can provide.Methods Focusing on patients exposed to paternal medication during the perinatal period,the clinical practice model of our hospital's clinical pharmacists consultation for paternal drug exposure was introduced.Furtherly,a retrospective survey on the information of consultants was conducted and the characteristics of drug exposure were analysed in this population,and a comparation made with data from foreign teratogenic information service centers.Results From October 2017 to September 2022,leveraging our hospital's Pregnancy Registration Platform for Medication,clinical pharmacists provided pharmaceutical consultation services for 404 outpatient cases of paternal exposure,and established a standardized consultation flow.Paternal exposure counseling accounted for 3.6% of cases,with medication use during an unplanned pregnancy being the most common situation(79.2% ).The average number of exposed drugs was(2.6±1.7).The top five types of drugs consulted were antimicrobials,Chinese traditional patent medicine,cardiovascular system drugs,digestive system drugs and endocrine system drugs.The five most frequently used drugs were cephalosporins,sartans,entecavir,levofloxacin and metformin.Effective follow-up was conducted on 261 cases,with a follow-up rate of 81.6%,and no congenital abnormal signals were indicated after exposure to the father's medication.Conclusion Pateral drug exposure in China has received little attention,with very limited research evidence available.Clinical pharmacists providing evidence-based drug risk assessment and medication advice to the public and healthcare professionals,along with conducting observational studies based on cases,are of significant importance in promoting the the safe use of paternal medications.
