Status Investigation on Management of Off-label Drug Use in Tertiary Hospitals of Guizhou Province
10.3870/j.issn.1004-0781.2024.09.029
- VernacularTitle:贵州省三级医疗机构超说明书用药管理情况调查
- Author:
Rui ZHANG
1
,
2
;
Pengpeng KAN
;
Jiaxing ZHANG
;
Juan XIE
;
Qi CHEN
;
Linfang HU
;
Huaye ZHAO
;
Junjie LAN
;
Jiaxue WANG
;
Shuimei SUN
;
Songsong TAN
Author Information
1. 贵州省人民医院药剂科,贵阳 550002
2. 贵州省药事管理质量控制中心,贵阳 550002
- Keywords:
Off-label drug use;
Pharmacy administration;
Tertiary hospitals of Guizhou province
- From:
Herald of Medicine
2024;43(9):1519-1524
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the current status of off-label drug use(OLDU)management in tertiary hospitals of Guizhou province and to provide baseline evidence for developing a unified administration regulation for OLDU in Guizhou province.Methods In line with the relevant policies and regulations,a questionnaire including basic information about the person filling out the form,basic information about the hospitals,and information about OLDU was developed.The questionnaire was sent to 84 tertiary hospitals in Guizhou province through the Wenjuanxing.Results A total of 84 questionnaires were distributed and recovered,with a response rate of 100.00%.Of the 84 hospitals,77 had OLDU,of which 68(88.31%)had established a management system for OLDU.Among the 77 hospitals with OLDU,65(84.42%),42(54.55%),58(75.32%),36(46.75%),15(19.48%),and 21(27.27%)hospitals respectively,required approval from the Committee on Drug Administration and Pharmacotherapy before OLDU,restricted the qualifications of doctors prescribing OLDU,required informed consent from patients or their families before OLDU,recorded the matters and reasons in the medical records of patients treated with OLDU,followed up patients in their files and evaluated the reasonableness of the OLDU,and carried out special reviews for OLDU.Only 30(38.96%)hospitals have set up a catalogue of OLDUs,and 58(75.32%)hospitals have urgent needs to set up a unified provincial catalogue of OLDUs.Conclusion The pharmacy administration level of OLDU in tertiary hospitals of Guizhou province is relatively low,so there is an urgent need to establish a unified OLDU management system and medication catalog.
