Individualized Pharmaceutical Care for Digoxin Poisoning in Patient with Dilated Cardiomyopathy
10.3870/j.issn.1004-0781.2024.08.023
- VernacularTitle:扩张型心肌病患者地高辛中毒的药学监护
- Author:
Xiaojuan YANG
1
;
Lan WANG
;
Shubin CUI
;
Zhaoshuai JI
;
Qiantai MAO
;
Weiwei SONG
;
Chao AI
Author Information
1. 清华大学附属北京清华长庚医院/清华大学临床医学院药学部,北京 102218
- Keywords:
Digoxin;
Dilated cardiomyopathy;
Therapeutic drug monitoring(TDM);
Medication therapy management(MTM);
Pharmaceutical care
- From:
Herald of Medicine
2024;43(8):1321-1325
- CountryChina
- Language:Chinese
-
Abstract:
Objective To introduces drug treatment and individualized pharmaceutical care for a patient with dilated cardiomyopathy digoxin poisoning and provides ideas for pharmaceutical care.Methods The pharmacist used therapeutic drug management to analyze the course of drug treatment before and after hospitalization,combined with therapeutic drug monitoring and drug-gene detection,to analyze the causes of poisoning in digoxin from the perspectives of underlying diseases,polymor-phism,drug dosage,combination of drugs,physiological and other pathological factors,and to assist in clinical drug reformula-tion and optimization of drug treatment regimens.Results The clinician accepted the clinical pharmacist's suggestion.The pa-tient had a good prognosis,and digoxin poisoning did not occur in the later period.Conclusion This case provides a feasible treatment for dilated cardiomyopathy and other patients with digoxin intoxication;it can be used as a reference for the prevention and treatment of digoxin poisoning and provide a new direction for the development of hospital pharmaceutical care and pharma-ceutical professionals.