Research Progress on Deformable Nanocapsular Carrier-Transferosomes in Transdermal Preparations
10.3870/j.issn.1004-0781.2024.08.020
- VernacularTitle:可变形纳米囊载体——传递体在透皮制剂中的研究进展
- Author:
Ziqian LI
1
;
Xiao CHEN
;
Deying CAO
;
Yunjie DANG
Author Information
1. 河北医科大学药剂学教研室,石家庄 050017
- Keywords:
Transdermal drug delivery;
Transfersomes;
Lipid vesicles
- From:
Herald of Medicine
2024;43(8):1302-1308
- CountryChina
- Language:Chinese
-
Abstract:
Transdermal preparations can effectively avoid the first-pass effect and have good clinical medication compliance.Transfersomes(TF),as a novel deformable lipid vesicle with good skin penetration efficiency and encapsulation rate,exert their efficacy by maintaining stable plasma concentration in vivo.They are novel transdermal absorption preparations with great development prospects.This article summarized the current research on TF,including the preparation technology,evaluation indexes,and clinical application,and prospected its research prospects.