Research Progress of Microneedle Delivery System in the Treatment of Skin Tumors
10.3870/j.issn.1004-0781.2024.08.011
- VernacularTitle:微针递送系统在皮肤肿瘤治疗中的研究进展
- Author:
Yiting LUO
1
;
Ting YU
;
Yue QIU
;
Longfei LIAO
;
Xue MA
;
Hongtao XIAO
;
Tingting QI
Author Information
1. 四川省肿瘤临床医学研究中心,四川省肿瘤医院·研究所,四川省癌症防治中心,电子科技大学附属肿瘤医院药学部,成都 610041
- Keywords:
Microneedles delivery system;
Skin tumors;
Drug delivery
- From:
Herald of Medicine
2024;43(8):1235-1244
- CountryChina
- Language:Chinese
-
Abstract:
As an emerging drug delivery technology,microneedles can puncture the skin's stratum corneum to create micron-sized conduits,painlessly,minimally invasive,and efficiently deliver drugs into viable epidermis or dermis for local or systemic therapeutic effects.This paper reviews the current clinical trials of microneedles used in the treatment of various diseases,elaborates on the characteristics of various types of microneedles,and summarizes the latest research progress of microneedles used to treat skin tumors,including chemotherapy,photothermal and photodynamic therapy,immunotherapy,gene therapy,and combination therapy.This review provides ideas and directions for further research on microneedles in treating skin tumors.