Evaluation of Effectiveness of Pharmaceutical Care Model for Patients with Hepatitis B Cirrhosis Based on Medication Therapy Management Combined with PCNE Classification System
10.3870/j.issn.1004-0781.2024.06.023
- VernacularTitle:药物治疗管理结合PCNE分类系统对乙型肝炎肝硬化患者的药学服务效果评价
- Author:
Lu XU
1
;
Mengying LI
;
Xingbei ZHOU
;
Yaping JIANG
;
Yuan WEI
;
Danjuan XU
;
Ningxun ZOU
Author Information
1. 江苏省镇江市第三人民医院(江苏大学附属镇江三院)药剂科,镇江 212000
- Keywords:
Clinical pharmacists;
Medication therapy management;
Pharmaceutical care network Europe drug-related problem classification;
Effectiveness assessment
- From:
Herald of Medicine
2024;43(6):987-992
- CountryChina
- Language:Chinese
-
Abstract:
Objective To provide pharmaceutical care for patients with hepatitis B cirrhosis by using the medication therapy management(MTM)model combined with Pharmaceutical Care Network Europe(PCNE),and to analyze the effectiveness of pharmaceutical care from clinical efficacy,safety,humanistic effect and drug-related problems(DRPs).Methods Patients with hepatitis B cirrhosis were randomly divided into the pharmaceutical care group and the control group who received only conventional treatment.Clinical pharmacists used MTM combined with PCNE to provide pharmaceutical care in the pharmaceutical care group.Economic effects,clinical indicators,safety,medication compliance and quality of life were compared between the two groups during the treatment and follow-up period.DRPs were analyzed in the pharmaceutical care group.Results The cost-utility ratio and clinical indicators in the pharmaceutical care group were better than those in the control group,and the adverse drug reactions of the former were statistically significant compared with the latter at the three months follow-up,and medication compliance and quality of life were statistically significant after intervention and during follow-up(P＜0.05).There were 52 DRPs in the pharmaceutical care group,mainly in the category of poor treatment outcome.The main reasons were poor drug selection and excessive usage and dosage.There were 46 DRPs accepted by intervention,and 45 DRPs were completely and partially solved.Conclusion The pharmaceutical care model of MTM combined with PCNE classification system for patients with hepatitis B cirrhosis played a positive role in the treatment and follow-up period.
