Comparison of long-term prognosis after percutaneous coronary intervention in patients with type 2 diabetes mellitus, impaired glucose tolerance and non-diabetes mellitus
10.3760/cma.j.cn115682-20200930-05594
- VernacularTitle:2型糖尿病、糖尿病前期、非糖尿病患者PCI术后远期预后的比较
- Author:
Lina WEN
1
;
Jingjing ZHANG
;
Yingsheng ZHOU
;
Yinan ZHAO
;
Jing TIAN
;
Xiaopo WU
;
Liping MA
;
Zuqian LU
Author Information
1. 首都医科大学附属北京安贞医院内分泌科 100029
- Keywords:
Diabetes mellitus, type 2;
Impaired glucose tolerance;
Percutaneous coronary intervention;
Major adverse cardiovascular events
- From:
Chinese Journal of Modern Nursing
2021;27(15):2050-2054
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore effects of impaired glucose tolerance (IGT) and type 2 diabetes mellitus (T2DM) on the 5-year prognosis after percutaneous coronary intervention (PCI) for coronary heart disease.Methods:A total of 165 patients receiving PCI from December 2011 to September 2013 were selected by the convenient sampling method. According to the results of oral glucose tolerance test, they were divided into T2DM group (54 cases) , IGT group (52 cases) , and non-diabetes mellitus (NDM) group (59 cases) . The patients were followed up in the outpatient clinic after discharge and recorded the occurrence of major adverse cardiovascular events (MACE) of patients within 5 years after PCI, including cardiogenic death, non-fatal reinfarction, non-fatal stroke and re-hospitalization for heart failure.Results:The 5-year follow-up results showed that 72 patients had MACE, of which 15 died of cardiogenic death, 11 were admitted to the hospital due to heart failure, 5 had non-fatal stroke and 41 had non-fatal reinfarction. Among the 72 patients with MACE, there were 17 cases in the NDM group, 30 cases in the IGT group and 25 cases in the T2DM group. The IGT group was higher than the NDM group, and the difference was statistically significant ( P<0.05) , but there was no statistically significant difference between the IGT group and the T2DM group ( P>0.05) . Among the 41 non-fatal reinfarction patients, there were 10 cases in the NDM group, 19 cases in the IGT group and 12 cases in the T2DM group. The IGT group was higher than the NDM group and the T2DM group, and the differences were statistically significant ( P<0.05) . Conclusions:IGT increases the risk of myocardial infarction in patients after PCI, which is a risk factor for MACE events.