Re-evaluation of the systematic review of vitamin D in prevention of falls in the elderly
10.3760/cma.j.cn115682-20200831-05125
- VernacularTitle:维生素D预防老年人跌倒的系统评价再评价
- Author:
Dan ZHAO
1
;
Nannan HU
;
Hong GUO
Author Information
1. 北京中医药大学护理学院 100102
- Keywords:
Aged;
Accidental fall;
Vitamin D;
Re-evaluation of systematic review
- From:
Chinese Journal of Modern Nursing
2021;27(14):1841-1847
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To re-evaluate the methodological quality and quality of evidence of the systematic review of vitamin D in prevention of falls in the elderly.Methods:Cochrane Library, PubMed, Web of Science, Embase, CNKI, WanFang Database, China Biology Medicine Disc and VIP databases were searched by computer to collect systematic reviews or Meta-analysis on vitamin D in prevention of falls in the elderly, and the references included in the literature were searched manually. The time limit was from the construction of the database to March 2020. Two researchers independently screened and extracted data, and they used AMSTAR 2 Scale and Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system to evaluate the methodology and evidence quality of the included studies.Results:A total of 13 systematic reviews or Meta-analysis were included. AMSTAR 2 evaluation results showed that the methodological quality of 11 studies was extremely low, and that of 2 studies was high. Grade evaluation results showed that among the 21 outcome indicators included in the evaluation, 8 were extremely low quality, 7 were low quality, 6 were medium quality, and no evidence was of high quality.Conclusions:Current studies have shown that vitamin D has a certain effect in preventing falls in the elderly, but the methodological quality of most studies is relatively low and the quality of evidence is generally reliable. The adverse reactions of vitamin D supplementation are also quite heterogeneous. Future research still needs to carry out large-scale and high-quality research to clarify the role and adverse effects of vitamin D.
