Correlation Between Blood Pressure Dropping Rate at Night and HRV and DC in Female Patients with Essential Hypertension
10.11969/j.issn.1673-548X.2024.09.010
- VernacularTitle:女性原发性高血压患者夜间血压下降率与HRV及DC的相关性研究
- Author:
Yinmei ZHANG
1
;
Wenting WANG
;
Lulu ZHU
Author Information
1. 730030 兰州大学第二临床医学院
- Keywords:
Essential hypertension;
Female;
Autonomic nerve;
Heart rate variability;
Deceleration capacity of heart rate;
Meno-pause
- From:
Journal of Medical Research
2024;53(9):44-49
- CountryChina
- Language:Chinese
-
Abstract:
Objective Using the methods of heart rate variability(HRV)and deceleration capacity of heart rate(DC),which mo-nitor cardiac autonomic nervous function,to study the correlation between the nocturnal blood pressure dropping rate and cardiac autonom-ic nervous function in female patients with essential hypertension,and to explore the related factors affecting the nocturnal blood pressure dropping rate in female patients with essential hypertension.Methods A total of 187 female patients with essential hypertension admitted to the Second Hospital of Lanzhou University from January 2019 to August 2023 were selected.General data,nocturnal blood pressure dropping rate,HRV time domain parameters(SDNN,SDANN,SDNNI,PNN50)and DC were collected.According to the nocturnal sys-tolic blood pressure dropping rate,they were divided into three groups:dipper group,non-dipper group,and reverse dipper group.The differences of general data and 24-hour,daytime and nighttime mean blood pressure and heart rate,HRV time domain parameters and DC values among three groups were compared,and the correlation between the nocturnal blood pressure dropping rate and HRV time do-main parameters,DC values and other general data was analyzed,and the factors affecting the nocturnal blood pressure dropping rate of fe-male patients with essential hypertension were analyzed by simple and multiple linear regression.Results The nocturnal blood pressure dropping rate in female patients with essential hypertension was linearly positive correlated with SDNN,SDANN,SDNNI and DC values(β were 0.235,0.016,0.102,0.493,P＜0.05),and linearly negative correlated with menopause(β=-3.798,P＜0.05).The re-sults of multiple linear regression analysis showed that SDNN,menopause,age,diabetes were the factors affecting the nocturnal blood pressure dropping rate.Conclusion In female patients with essential hypertension,the imbalance of cardiac autonomic nerve regulation,menopause,age and diabetes are the main risk factors affecting the nocturnal blood pressure dropping rate.
