Significance of Muscle Mass Evaluation for Nutritional Assessment and Diagnosis in Patients with COPD
10.11969/j.issn.1673-548X.2024.08.023
- VernacularTitle:COPD患者肌肉质量评价对营养评估及诊断的意义
- Author:
Alima
1
;
Dejun SUN
;
Depeng LI
Author Information
1. 010017 呼和浩特,内蒙古自治区人民医院
- Keywords:
Chronic obstructive pulmonary disease;
Muscle mass;
Nutritional assessment
- From:
Journal of Medical Research
2024;53(8):120-125,131
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the muscle and fat status of patients with chronic obstructive pulmonary disease(COPD),and ex-plore the correlation with disease development.Methods One hundred and eighteen patients with COPD(study group)and 97healthy subjects(control group)were selected.Body mass index(BMI),fat-free weight(FFM),skeletal muscle index(SMM),appendicular skeletal muscle height index(ASMHI),percent body fat(PBF),visceral fat area(VFA),waist circumference(WaistCir),upper arm circumference(AC),upper arm muscle circumference(AMC),phase angle(PA)and other indicators were measured by bioelectrical impedance and height scale,and were compared and analyzed between the two groups.At the same time,the basic information,laboratory indicators and admission pulmonary function test data of patients with COPD were collected for correlation analysis.To identify the optimal cut-off value for FFM in the diagnosis of malnutrition according to the Global Leadership Initiative on Malnutrition(GLIM)diagnostic criteria.Results The FFM,SMM,lower limb muscles,ASMHI and AMC in study group were lower than those in the control group(P＜0.05).The BMI,PBF and VFA of the patients in the smoking cessation group were higher than those in the continuous smoking group(P＜0.05).The forced expiratory volume in one second(FEV1),forced expiratory volume in one second in predicted(FEV1％pred),forced vital capacity(FVC)and FEV1/FVC were lower in patients with low-ASMHI(P＜0.05).Neutrophil-lymphocyte ratio(NLR)was higher in the low-ASMHI group than taht in the normal ASMHI group(P＜0.05).The results of GLIM diagnostic showed that 50.8％of COPD patients were malnourished.The optimal cut-off value of FFM for predicting malnutrition was 47.85kg.Conclusion Patients with COPD are prone to unbalanced distribution of muscle and fat.The consistency of FFM with the diagnosis of GLIM has impor-tant clinical significance for the early identification and diagnosis of malnutrition.
