Impact of fear of disease progression on quality of life in kidney transplant recipients: the chain mediating effect of intrusive thinking and psychological distress
10.3760/cma.j.cn115682-20200708-04279
- VernacularTitle:肾移植受者疾病进展恐惧感对生命质量的影响：侵袭性思维与心理困扰的链式中介作用
- Author:
Tian ZHANG
1
;
Hailing ZHANG
;
Mengyuan CHENG
;
Li YUAN
;
Yueyan FANG
;
Aiqin CHU
Author Information
1. 中国科学技术大学附属第一医院（安徽省立医院）器官移植中心，合肥 230001
- Keywords:
Kidney transplantation;
Quality of life;
Fear of disease progression;
Intrusive thinking;
Psychological distress;
Mediation effect
- From:
Chinese Journal of Modern Nursing
2021;27(10):1261-1267
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the chain mediating effect of intrusive thinking and psychological distress on the fear of disease progression and quality of life of kidney transplant recipients, with a view to providing scientific theoretical guidance for effective psychological interventions for kidney transplant recipients.Methods:This study is a cross-sectional study. Convenience sampling was used to select 312 kidney transplant recipients who were followed up in the Outpatient Clinic of the First Affiliated Hospital of University of Science and Technology of China from January to May 2019. Patients were investigated with the General Information Questionnaire, the Fear of Progression Questionnaire, the Impact of Events Scale-Revised Intrusion Subscale, Distress Thermometer and 12-Item Short-Form Health Survey Questionnaire. Mplus 8.3 was used to construct and verify multiple intermediary models.Results:A total of 296 kidney transplant recipients were included in this study. In quality of life, the mental health score was (49.58±8.97) , and the physical health score was (49.90±9.17) . Fear of disease progression, intrusive thinking and psychological distress were all negatively correlated with mental health and physical health of quality of life (the r values were -0.453 to -0.401, P<0.01) . The mediating effect of fear of disease progression on the quality of life was established. The total mediating effect value was -0.273, and the specific mediating effect of intrusive thinking accounted for 46.52%, and the specific mediating effect of psychological distress accounted for 41.76%. The chain mediating effect of intrusive thinking and psychological distress between fear of disease progression and quality of life accounted for 11.72%. Conclusions:The intrusive thinking and psychological distress of kidney transplant recipients are established as a chain mediation between the fear of disease progression and the quality of life. While paying attention to patients' fear of disease, clinical staff should pay attention to assessing patients' intrusive thinking and psychological distress, and take targeted measures to reduce the impact of fear of disease progression on the quality of life.
