Factors Associated with Comorbid ADHD in Children with Tic Disorders and Mediation Effect Analysis
10.11969/j.issn.1673-548X.2024.05.023
- VernacularTitle:抽动障碍患儿共患ADHD的影响因素及中介效应分析
- Author:
Fang LIU
1
;
Baozhen YAO
;
Hong LIU
Author Information
1. 430060 武汉大学人民医院儿科
- Keywords:
Tic disorders;
ADHD;
Mediation effect;
Path analysis;
Children
- From:
Journal of Medical Research
2024;53(5):112-117
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the influencing factors associated with comorbid attention deficit hyperactivity disorder(ADHD)in children with tic disorders(TD)and the mediation effect in the path relationship.Methods The clinical data,demographic,and family environmental information of 363 children with TD were investigated and collected,and the study was carried out using multivariate Logistic regression analysis,path analysis,and mediation effect analysis.Results Parenting pattern of indulgence(OR=2.59),moder-ate/severe TD(OR=25.92),and combined behavioral problems(OR=3.72)were the risk factors for TD comorbid ADHD.The results of mediation effect analysis showed that TD severity partially mediated the association between TD type and behavioral problems,and the effect size was 14.34％;behavioral problems partially mediated the association between TD severity and comorbid ADHD,and the effect size was 6.49％;behavioral problems partially mediated the association between parenting pattern and comorbid ADHD,and the effect size was 24.14％.Conclusion TD with comorbid ADHD was closely associated with family environmental and clinical factors.In the process of TD diagnosis and treatment,the influence of the diseases themselves,comorbidities,and mediators should be fully considered.
