The value of 7-point peripheral blood glucose in predicting asymptomatic hypoglycemia at night in elderly patients with type 2 diabetes mellitus
10.3760/cma.j.cn115682-20200503-03137
- VernacularTitle:7点末梢血糖值预测老年2型糖尿病患者夜间无症状低血糖的价值
- Author:
Yingrui WANG
1
;
Zhenyun GUO
;
Haiyan ZHAO
;
Kun ZHANG
Author Information
1. 河南省新乡市中心医院内分泌科 453000
- Keywords:
Diabetes mellitus;
Aged;
Asymptomatic hypoglycemia at night;
Peripheral blood glucose;
Continuous glucose monitoring
- From:
Chinese Journal of Modern Nursing
2021;27(2):232-235
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the value of blood glucose at different time points in the 7-point peripheral blood glucose spectrum in predicting asymptomatic hypoglycemia at night in elderly patients with type 2 diabetes mellitus (T2DM) based on continuous glucose monitoring system (CGMS) .Methods:From January to October 2019, convenience sampling was used to select 225 elderly T2DM patients who were hospitalized in Xinxiang Central Hospital. We monitored the peripheral blood glucose at 7 time points after admission, and performed 72-hour continuous glucose monitoring (CGM) simultaneously. We investigated the occurrence of night hypoglycemia of patients, and divided patients into night symptomatic hypoglycemia group and night asymptomatic hypoglycemia group according to the results. We compared the hypoglycemia related indicators of two groups, drew the receiver operating characteristic (ROC) curve, calculated the area under the curve (AUC) to determine the best cut-point value of each indicator and the occurrence of asymptomatic hypoglycemia at night.Results:In the CGM of 225 patients, 74 cases had hypoglycemia at night, and the incidence was 32.89%, and 34 cases of them had asymptomatic hypoglycemia at night, accounting for 45.95% (34/74) . The fasting blood glucose, blood glucose after dinner and before bedtime of patients in night asymptomatic hypoglycemia group were lower than those of night symptomatic hypoglycemia group. The best cut-off points of blood glucose before bedtime and fasting blood glucose for predicting asymptomatic hypoglycemia at night were 6.9 mmol/L and 6.0 mmol/L respectively, and the AUC were 0.822 and 0.651 respectively.Conclusions:We should be alert to the occurrence of asymptomatic hypoglycemia at night in elderly patients with T2DM. Blood glucose before bedtime <6.9 mmol/L or fasting blood glucose <6.0 mmol/L indicates an increased risk of asymptomatic hypoglycemia at night.
