Time course of end-tidal desflurane concentration during delivery and elimination according to the type and location of filters in a semi-closed circuit system.
10.4097/kjae.2015.68.4.392
- Author:
Sung Wook PARK
1
;
Jun Young CHUNG
;
Eun Jin MOON
;
Young Jin KANG
;
Jong Man KANG
Author Information
1. Department of Anesthesiology and Pain Medicine, Kyung Hee University Hospital, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Concentration;
Desflurane;
Filter;
Tidal volume
- MeSH:
Anesthesia;
Extremities;
Lung;
Respiration;
Tidal Volume
- From:Korean Journal of Anesthesiology
2015;68(4):392-396
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The aim of this study was to determine whether the end-tidal concentration of desflurane would be affected by a breathing circuit system filter attached at two different positions in anesthetic breathing circuit systems. METHODS: An artificial lung was ventilated under five different conditions. The first group was without any filter or desflurane (n = 5, sham), the second was with desflurane but without any filter (n = 10, control), the third group had a bacterial filter on the expiratory limb (n = 10), and the fourth and fifth groups had a viral/bacterial filter added on the expiratory limb (n = 10) or at the Y-piece of the breathing circuit (n = 10), respectively. In all groups except the sham, administration of 10% desflurane was performed for 5 minutes and then stopped for 5 minutes. RESULTS: The mean (SD) end-tidal concentration of desflurane for the groups described above peaked at 0 (0), 9.8 (0.1), 9.8 (0.1), 8.5 (0.1), and 6.7% (0.1) (P < 0.001), respectively. There was no difference in the desflurane concentrations and the expired tidal volume over time between the control and bacterial group, but there was a significant difference between the control and the fourth and fifth groups (P < 0.001). CONCLUSIONS: Filters can affect the expiratory desflurane concentration during anesthesia.
