Application of moxibustion pretreatment on bone marrow suppression in cancer patients after chemotherapy
10.3760/cma.j.cn115682-20200717-04466
- VernacularTitle:艾灸预处理在癌症患者化疗后骨髓抑制中的应用
- Author:
Chengcheng CHEN
1
;
Songyi NING
;
Jing YANG
;
Jiejie SUN
;
Tingting ZHANG
;
Yongping AO
Author Information
1. 江苏大学医学院护理学院，镇江 212013
- Keywords:
Neoplasms;
Drug therapy;
Moxibustion;
Pretreatment;
Bone marrow suppression
- From:
Chinese Journal of Modern Nursing
2021;27(1):38-43
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of moxibustion pretreatment on bone marrow suppression in cancer patients after chemotherapy, so as to provide a basis for clinical nursing.Methods:From May 2019 to May 2020, we selected 70 cancer patients who met the criteria in the Oncology Department of a ClassⅢ Grade A hospital in Xuzhou City, Jiangsu Province by convenient sampling. There were 65 patients who finally completed the trial including moxibustion pretreatment group ( n=20) , moxibustion group ( n=22) , and control group ( n=23) . All three groups received regular chemotherapy. Patients in moxibustion pretreatment group received moxibustion 7 days before the start of chemotherapy, once a day, for 14 days; patients in moxibustion group were treated with moxibustion at the beginning of chemotherapy, once a day, for 7 days; control group carried out conventional chemotherapy. We compared the white blood cell count, neutrophil count, incidence and degree of bone marrow suppression, and the use of recombinant human granulocyte colony stimulating factor among the three groups. Results:The white blood cell and neutrophil counts of the three groups were compared between the groups and at different times, and the differences were statistically significant ( P<0.05) . The incidences of bone marrow suppression on the seventh and fourteenth day after chemotherapy of the three groups of patients were compared between the groups and at different times with statistical differences ( Wald χ2groups=6.628, P=0.036; Wald χ2times=43.018, P<0.001) . A total of 7, 14 days after chemotherapy, there were statistical differences in the use of recombinant human granulocyte colony stimulating factor in patients among the three groups ( P<0.05) . Conclusions:Moxibustion pretreatment can stabilize the white blood cell and neutrophil counts of cancer patients after chemotherapy, reduce the incidence of bone marrow suppression, the degree of bone marrow suppression as well as the use of recombinant human granulocyte colony stimulating factor.
