Curative effects of ginger combined with tropisetron on chemotherapy-induced nausea and vomiting of breast cancer
10.3760/cma.j.cn115682-20200213-00664
- VernacularTitle:生姜联合托烷司琼对乳腺癌化疗相关性恶心呕吐的疗效
- Author:
Cuifang LIU
1
;
Yali SU
;
Meng ZHAO
;
Han YOU
;
Xinyu WANG
Author Information
1. 首都医科大学附属北京天坛医院乳腺外科 100070
- Keywords:
Antineoplastic combined chemotherapy protocols;
Ginger slice;
Nausea;
Vomiting
- From:
Chinese Journal of Modern Nursing
2020;26(33):4657-4660
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the curative effect of ginger combined with tropisetron on preventing nausea and vomiting caused by chemotherapy in patients with breast cancer.Methods:80 patients with breast cancer who received first chemotherapy from Beijing Tiantan Hospital from April 2019 to December 2019 were selected by the convenient sampling method. According to the random number table method, they were divided into the control group and the intervention group, with 40 cases in each group. The control group received intravenous tropisetron before routine chemotherapy to prevent nausea and vomiting. On this basis, patients in the intervention group took slices of fresh ginger under the tongue 30 min before chemotherapy and applied the slices of fresh ginger to Shenque acupoint and Neiguan acupoint. The degree of nausea and vomiting after chemotherapy and compliance with chemotherapy were compared between the two groups.Results:On 0 to 5 d after chemotherapy, there were 7 patients with nausea of grade Ⅱ and Ⅲ in the intervention group and 18 patients with nausea of grade Ⅱ and Ⅲ in the control group. There were 4 patients with vomiting of grade Ⅱ and Ⅲ in the intervention group and 18 patients with vomiting of gradeⅡ and Ⅲ in the control group. There were statistically significant differences in the degrees of nausea and vomiting between the two groups ( Z=-2.980, -4.151; P<0.05) . There was no statistically significant difference in chemotherapy compliance between the two groups ( P>0.05) . Conclusions:Ginger in mouth and ginger point application combined with tropisetron can effectively alleviate chemotherapy-induced nausea and vomiting symptoms.
