Simultaneous determination of primary volatile components in Tibetan medicine Bawei Chenxiang powders by GC
10.12173/j.issn.1005-0698.202403035
- VernacularTitle:GC法同时测定藏药八味沉香散中挥发性指标成分含量
- Author:
Meiyun SU
1
,
2
,
3
;
Pei WANG
;
Yanping LIU
;
Hebing XIE
;
Danzeng BAIMA
Author Information
1. 安徽中医药大学药学院(合肥 230012)
2. 南通市海门长三角药物高等研究院(江苏南通 226133)
3. 江苏神猴医药研究有限公司(江苏南通 226133)
- Keywords:
Bawei Chenxiang powders;
Volatile components;
Octyl acetate;
Benzylacetone;
Myristicin;
Dehydrocostus lactone;
GC;
Content determination
- From:
Chinese Journal of Pharmacoepidemiology
2024;33(11):1247-1253
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a GC method for simultaneous determination of volatile index components of octyl acetate,benzylacetone,myristicin and dehydrocostus lactone in Tibetan medicine Bawei Chenxiang powders.Methods A GC method was used with octyl acetate,benzylacetone,myristicin and dehydrocostus lactone as indicator components,SH-WAX capillary column(30 m×0.25 mm,0.25 μm)and temperature programming were used,the carrier gas was nitrogen,the inlet temperature was 220 ℃,the detector temperature was 240 ℃,with split injection volume of 1 μL.Results The concentrations of octyl acetate,benzylacetone,myristicin and dehydrocostus lactone showed a good linear relationship with peak area(r＞0.999 5)in the range of 12.44-124.43 μg·mL-1,2.90-29.01 μg·mL-1,15.95-159.45 μg·mL-1,15.62-156.15 μg·mL-1,respectively;the average recovery rates were 100.40％(RSD=1.55％),97.80％(RSD=1.41％),99.50％(RSD=0.77％)and 99.50％(RSD=0.85％)(n=6).Conclusion The method has good specificity,precision,repeatability and accuracy,and can be used for the determination of volatile index components in Bawei Chenxiang powders.
