Clinical pharmacists participated in the drug therapy and pharmaceutical care of a patient with Crohn's disease complicated with erythema multiforme
10.12173/j.issn.1005-0698.202407014
- VernacularTitle:临床药师参与1例克罗恩病合并多形红斑患者的药物治疗与监护
- Author:
Binbin LI
1
,
2
;
Cuilin XU
;
Naizhong HU
;
Xiaofei REN
;
Yanyan WANG
Author Information
1. 玉林市第一人民医院药学部(广西玉林 537000)
2. 安徽医科大学第一附属医院药剂科(合肥 230000)
- Keywords:
Crohn's disease;
Erythema multiforme;
Infliximab;
Ustekinumab;
Extraintestinal manifestations;
Pharmaceutical care
- From:
Chinese Journal of Pharmacoepidemiology
2024;33(9):1074-1080
- CountryChina
- Language:Chinese
-
Abstract:
Clinical pharmacists participated in the drug therapy and monitoring of a patient with Crohn's disease complicated with erythema multiforme.The patient,who had a previous diagnosis of Crohn's disease for many years and had been treated with infliximab to date,was admitted to the hospital with a scattered rash on the peripheral skin,normal stools,and fecal calprotectin＞1 800 μg-g-1,by collecting the patient's medical history,reviewing domestic and foreign literature,the clinical pharmacist assisted the physician in ruling out drug factors,and making a definitive diagnosis of Crohn's disease complicated with extraintestinal manifestations.Taking into account the patient's condition and guideline recommendations,the clinical pharmacist assisted doctors to adjust medication regimen,and determined that the next step in the patient's treatment program was ustekinumab combined with glucocorticoids therapy,and continuously monitoring the patient's condition.The patient's condition was effectively controlled immediately before discharge,with marked improvement in erythema multiforme,and the patient was followed up 3 months later with complete disappearance of erythema multiforme,normal bowel movements,and no specific discomfort.Since the extraintestinal manifestations of Crohn's disease are often similar to the adverse reactions caused by medications used in the treatment or other systemic diseases and disorders,it is necessary for the clinical pharmacist to assist the physician in screening.The case was studied and compiled with a view to providing references for the diagnosis and pharmacological treatment of such patients.
