Pharmaceutical care of postoperative recurrence of osteomyelitis in a patient with previous vancomycin pseudoallergy
10.12173/j.issn.1005-0698.202404056
- VernacularTitle:1例既往万古霉素假性过敏患者骨髓炎术后复发的药学监护
- Author:
Weiwei LUO
1
;
Jianfeng JIN
;
Qiong YANG
;
Panpan ZHENG
;
Liangfang ZHOU
;
Danni ZHONG
Author Information
1. 宁波市第六医院药学部(浙江宁波 315100)
- Keywords:
Vancomycin;
Pseudoallergic;
Red man syndrome;
Clinical pharmacist;
Osteomyelitis
- From:
Chinese Journal of Pharmacoepidemiology
2024;33(8):944-948
- CountryChina
- Language:Chinese
-
Abstract:
A patient with osteomyelitis who developed a rash after previous treatment with vancomycin was admitted to the hospital due to a recurrence of osteomyelitis.After admission,the orthopedic doctor intended to perform a"calcium sulfate vancomycin implantation surgery"on him.Clinical pharmacist identified the patient's previous rash reaction as red man syndrome(RMS)rather than genuine drug allergy.At the same time,in response to the clinical doubt of whether patients with previous RMS can undergo"calcium sulfate vancomycin implantation surgery",clinical pharmacists reviewed and analyzed the literature,and suggested that the surgery can continue under close monitoring.The patient did not experience RMS or allergic reactions after surgery,and the condition improved.In this paper,the clinical pharmacists started with the identification of RMS and rapid allergic reactions,reviewed the literature on the local use of vancomycin and the risk of RMS,and provide suggestions for subsequent treatment,and also provide references for clinical safe drug use and treatment of similar diseases.
